Claude Sonnet 4.6 vs GPT-5.4 Mini: 200K Tokens for Medical Video Scripts

Claude Sonnet 4.6 has been replaced by Claude Sonnet 5

The pricing shown below is for the older model and is kept for reference. If you are choosing a model today, use the current version — its rate and context window differ.

See current Claude Sonnet 5 pricing →  ·  All recent pricing changes

Claude Sonnet 4.6 vs GPT-5.4 mini
Complete Comparison: 200,000 input tokens × 8,000 output tokens
Comparison Mode
⚡ 20% Cached

Complete comparison of pricing, performance, and capabilities for 2 leading AI models with 20% Cached.

⚡ Caching Optimized (up to 90% savings) 📊 Batch API
Comparison Criteria Claude Sonnet 4.6
Anthropic
GPT-5.4 mini
OpenAI
Calculation Results (Current Inputs) (20% cached)
Input Tokens 200,000 200,000
Output Tokens 8,000 8,000
Cost Breakdown
Input Cost $0.150000Worst $0.037500 (rounded ~ $0.04)Best
Output Cost $0.030000Worst $0.009000Best
Unit Cost (Audio/OCR) $0.000000 $0.000000
Service Fees $0.000000 $0.000000
Total Cost $0.153000 (rounded ~ $0.15) Most Expensive $0.039750 Best Value
Processing Time 8 minutes, 14.76 seconds Slowest 7 minutes, 25.30 seconds Fastest
Tokens per Second 450Slowest 500Fastest
Time to First Token 200ms Worst 180ms Best
Cost per 1K tokens $0.000736Worst $0.000191Best
Tokens per Dollar 1,359,477Worst Value 5,232,704Best Value
Cost per 1 Million Tokens (Informational)
Input Cost / 1M (Base) $0.750000Worst $0.187500 (rounded ~ $0.19)Best
Output Cost / 1M (Base) $3.750000Worst $1.125000 (rounded ~ $1.13)Best
Input Cost / 1M (Optimized) $0.375000 (rounded ~ $0.38)Worst
Optimizations: 50.0% batch
$0.093750 (rounded ~ $0.09)Best
Optimizations: 50.0% batch
Output Cost / 1M (Optimized) $1.875000 (rounded ~ $1.88)Worst
Optimizations: 50.0% batch
$0.562500 (rounded ~ $0.56)Best
Optimizations: 50.0% batch
Capabilities & Advanced Features
Images Support ✓ Supported ✓ Supported
Caching Support
20
✓ Supported ✓ Supported
Batch API Support ✓ Supported ✓ Supported
Tool Usage Support ✓ Supported ✓ Supported
Scroll horizontally to see all data

🔄 Compare Different AI Models

1

First Model

2

Second Model

Select providers and models above, then click "Compare Models" to update the comparison.
All other parameters will be preserved from the current comparison.

Click Recalculate to update after making changes

Select AI Model

Claude Sonnet 4.6
AnthropicMax Context: 1,000,000 tokens
$3 / $15 per 1M tokens
Use Batch API (50% discount)
20%
Provider-specific multipliers applied after all calculations
Enable for cache discounts
Select platform to enforce context limits
Number of requests (max 1M). Summary view auto-enabled >10k.

Calculate Token Costs

$0.120000 Input Cost
$0.030000 Output Cost
$0.000000 Unit Cost
$0.000000 Search Cost
$0.000000 Request Fee
$0.000000 Tool Fee
$0.000000 Code Execution
208,000Total Tokens
$0.000736Cost per 1K
1,359,477Tokens per $
📊 Advanced Cost Breakdown

Processing Speed

8m 14s Processing Time
450 Tokens/Second
200ms Time to First Token
421 Effective Speed

Model Comparison

Select a model to see comparisons with competitors.

Model Information

Select a model to see detailed information.

🔄 Advanced Options

⚡ Optimization
Flat fee per session (e.g., $0.03 for Code Interpreter)
Hourly storage fee for cached data
First 50 hours free, $0.05/hour after

🧠 Reasoning & Thinking
Manual thinking tokens (billed at output rate)

🔧 Special Modes
Enable 6.0x Fast Mode multiplier

📚 Research & Citations
Enable $1.00/$4.00 rates + $10.00/1k search
Enable research tier pricing
Fee per source cited

🎤 Realtime Audio & Video
Session length for billing
📊 Multiple Models Detected: This page contains data for 2 models. See the detailed comparison table above, and switch between models using tabs below.

Claude Sonnet 4.6 Anthropic 1000000

$0.153000 (rounded ~ $0.15)
Total Cost
⚡ 20% Cached 📊 Batch API
👁️
Vision/Images
✓ Available
🎧
Audio Processing
✗ Not Available
🎥
Video Analysis
✗ Not Available
🔧
Tool Usage
✓ Available
📄
OCR Support
✗ Not Available
📊
Batch API
✓ Available
Caching
✓ Available
90% savings

💰 Total Cost Calculation (from Plugin)

Base Cost (No Optimizations) $0.180000 Input: $0.150000
Output: $0.030000
Optimized Cost $0.153000 (rounded ~ $0.15) Input: $0.150000
Output: $0.030000
Unit: $0.000000
Fees: $0.000000
Total Savings $0.027000 (rounded ~ $0.03) 15.0% discount

Advanced Cost Breakdown (from Plugin)

📊 Batch API
50.0% off
Asynchronous processing discount

Detailed Cost Analysis (from Plugin)

For 200,000 input tokens and 8,000 output tokens:

  • Input Cost: $0.150000
  • Output Cost: $0.030000
  • Total Cost: $0.153000 (rounded ~ $0.15)
  • Cost per 1K tokens: $0.000736
  • Tokens per dollar: 1,359,477 tokens
  • Context Window: 1000000 tokens

Speed & Performance Analysis

With a processing speed of 450 tokens per second and 200ms time to first token:

  • Processing Time: 8 minutes, 14.76 seconds
  • Latency: 200 milliseconds to first token
  • Base Throughput: 450 tokens/second
  • Effective Throughput: 421 tokens/second (temperature-adjusted)

Best Use Cases

Claude Sonnet 4.6 is best for complexhigh-accuracy medical narration. GPT-5.4 Mini is best for high-throughputiterative drafting.

Want this applied to YOUR actual stack?

This calculator shows the math for Claude Sonnet 4.6. Your decision needs more — current infrastructure, compliance requirements, actual workload patterns, volume tiers — that change which model is right for you.

Get a $39 personalized AI Architecture Audit. PDF tailored to your stack, delivered in under 60 seconds. 7-day no-questions-asked refund.

Get my instant AI audit — $39 →

GPT-5.4 mini OpenAI

$0.039750
Total Cost
⚡ 20% Cached 📊 Batch API
👁️
Vision/Images
✓ Available
🎧
Audio Processing
✗ Not Available
🎥
Video Analysis
✗ Not Available
🔧
Tool Usage
✓ Available
📄
OCR Support
✗ Not Available
📊
Batch API
✓ Available
Caching
✓ Available
90% savings

💰 Total Cost Calculation (from Plugin)

Base Cost (No Optimizations) $0.046500 (rounded ~ $0.05) Input: $0.037500 (rounded ~ $0.04)
Output: $0.009000
Optimized Cost $0.039750 Input: $0.037500 (rounded ~ $0.04)
Output: $0.009000
Unit: $0.000000
Fees: $0.000000
Total Savings $0.006750 (rounded ~ $0.01) 14.5% discount

Advanced Cost Breakdown (from Plugin)

📊 Batch API
50.0% off
Asynchronous processing discount

Detailed Cost Analysis (from Plugin)

For 200,000 input tokens and 8,000 output tokens:

  • Input Cost: $0.037500 (rounded ~ $0.04)
  • Output Cost: $0.009000
  • Total Cost: $0.039750
  • Cost per 1K tokens: $0.000191
  • Tokens per dollar: 5,232,704 tokens
  • Context Window: 400000 tokens

Speed & Performance Analysis

With a processing speed of 500 tokens per second and 180ms time to first token:

  • Processing Time: 7 minutes, 25.30 seconds
  • Latency: 180 milliseconds to first token
  • Base Throughput: 500 tokens/second
  • Effective Throughput: 467 tokens/second (temperature-adjusted)

Best Use Cases

Claude Sonnet 4.6 is best for complexhigh-accuracy medical narration. GPT-5.4 Mini is best for high-throughputiterative drafting.

Want this applied to YOUR actual stack?

This calculator shows the math for GPT-5.4 mini. Your decision needs more — current infrastructure, compliance requirements, actual workload patterns, volume tiers — that change which model is right for you.

Get a $39 personalized AI Architecture Audit. PDF tailored to your stack, delivered in under 60 seconds. 7-day no-questions-asked refund.

Get my instant AI audit — $39 →

✨ Market Recommendations AI Model Registry

← Back to Claude Sonnet 4.6
📋 Active Input Parameters
Input Tokens: 200,000
Output Tokens: 8,000
Batch API: Enabled (50% discount)
Cached Tokens: 20%
Rank AI Model & Provider Total Cost vs Claude Sonnet 4.6 vs GPT-5.4 mini
🏆 Devstral Small 2
Mistral AI
$0.004700 Best Value ↓ 96.9% cheaper ↓ 88.2% cheaper
🥈 Gemini 3.1 Flash Lite
Google
$0.013250 (rounded ~ $0.01) ↓ 91.3% cheaper ↓ 66.7% cheaper
🥉 Nemotron 3 Super
NVIDIA
$0.013940 (rounded ~ $0.01) ↓ 90.9% cheaper ↓ 64.9% cheaper
#4 Gemini 3.5 Flash-Lite
Google
$0.017300 (rounded ~ $0.02) ↓ 88.7% cheaper ↓ 56.5% cheaper
#5 Gemini 2.5 Flash
Google
$0.017300 (rounded ~ $0.02) ↓ 88.7% cheaper ↓ 56.5% cheaper
#6 Devstral 2
Mistral AI
$0.018200 (rounded ~ $0.02) ↓ 88.1% cheaper ↓ 54.2% cheaper
#7 Mistral Large 3
Mistral AI
$0.023500 (rounded ~ $0.02) ↓ 84.6% cheaper ↓ 40.9% cheaper
#8 Gemini 3.8 Flash
Google
$0.038250 (rounded ~ $0.04) ↓ 75% cheaper ↓ 3.8% cheaper
#9 GPT-5.4 mini
OpenAI
$0.039750 ↓ 74% cheaper Same price
#10 Claude Haiku 4.5
Anthropic
$0.051000 (rounded ~ $0.05) ↓ 66.7% cheaper ↑ 28.3% more
#11 GPT-5.6 Luna
OpenAI
$0.053000 (rounded ~ $0.05) ↓ 65.4% cheaper ↑ 33.3% more
#12 Gemini 3.6 Flash
Google
$0.076500 (rounded ~ $0.08) ↓ 50% cheaper ↑ 92.5% more
#13 Gemini 3.5 Flash
Google
$0.079500 ↓ 48% cheaper ↑ 100% more
#14 Claude Sonnet 5
Anthropic
$0.102000 (rounded ~ $0.10) ↓ 33.3% cheaper ↑ 156.6% more
#15 Gemini 3.1 Flash
Google
$0.106000 (rounded ~ $0.11) ↓ 30.7% cheaper ↑ 166.7% more
#16 GPT-5.6 Terra
OpenAI
$0.132500 (rounded ~ $0.13) ↓ 13.4% cheaper ↑ 233.3% more
#17 Claude Opus 4.7
Anthropic
$0.255000 (rounded ~ $0.26) ↑ 66.7% more ↑ 541.5% more
#18 Claude Opus 5
Anthropic
$0.255000 (rounded ~ $0.26) ↑ 66.7% more ↑ 541.5% more
#19 Claude Opus 4.8
Anthropic
$0.255000 (rounded ~ $0.26) ↑ 66.7% more ↑ 541.5% more
#20 Claude Opus 4.6
Anthropic
$0.255000 (rounded ~ $0.26) ↑ 66.7% more ↑ 541.5% more
#21 GPT-5.4
OpenAI
$0.265000 (rounded ~ $0.27) ↑ 73.2% more ↑ 566.7% more
#22 GPT-5.4 Thinking
OpenAI
$0.265000 (rounded ~ $0.27) ↑ 73.2% more ↑ 566.7% more
#23 Gemini 2.5 Pro
Google
$0.265000 (rounded ~ $0.27) ↑ 73.2% more ↑ 566.7% more
#24 GPT-5.5 Instant
OpenAI
$0.265000 (rounded ~ $0.27) ↑ 73.2% more ↑ 566.7% more
#25 GPT-5.6 Sol
OpenAI
$0.265000 (rounded ~ $0.27) ↑ 73.2% more ↑ 566.7% more
#26 Grok 4.3
xAI
$0.360000 ↑ 135.3% more ↑ 805.7% more
#27 Grok 4.20 Beta
xAI
$0.360000 ↑ 135.3% more ↑ 805.7% more
#28 Gemini 3.1 Pro
Google
$0.400000 ↑ 161.4% more ↑ 906.3% more
#29 Claude Fable 5.1
Anthropic
$0.502500 (rounded ~ $0.50) ↑ 228.4% more ↑ 1164.2% more
#30 Claude Mythos 5.1
Anthropic
$0.502500 (rounded ~ $0.50) ↑ 228.4% more ↑ 1164.2% more
#31 Claude Fable 5
Anthropic
$0.510000 ↑ 233.3% more ↑ 1183% more
#32 Claude Mythos 5
Anthropic
$0.510000 ↑ 233.3% more ↑ 1183% more
#33 GPT-5.5
OpenAI
$1.000000 ↑ 553.6% more ↑ 2415.7% more
#34 GPT-6 Astra
OpenAI
$2.040000 ↑ 1233.3% more ↑ 5032.1% more
#35 GPT-6 Astra
OpenAI
$2.040000 ↑ 1233.3% more ↑ 5032.1% more
🏆

Devstral Small 2
Mistral AI

$0.004700
vs Claude Sonnet 4.6: ↓ 96.9%
vs GPT-5.4 mini: ↓ 88.2%
🥈

Gemini 3.1 Flash Lite
Google

$0.013250 (rounded ~ $0.01)
vs Claude Sonnet 4.6: ↓ 91.3%
vs GPT-5.4 mini: ↓ 66.7%
🥉

Nemotron 3 Super
NVIDIA

$0.013940 (rounded ~ $0.01)
vs Claude Sonnet 4.6: ↓ 90.9%
vs GPT-5.4 mini: ↓ 64.9%
#4

Gemini 3.5 Flash-Lite
Google

$0.017300 (rounded ~ $0.02)
vs Claude Sonnet 4.6: ↓ 88.7%
vs GPT-5.4 mini: ↓ 56.5%
#5

Gemini 2.5 Flash
Google

$0.017300 (rounded ~ $0.02)
vs Claude Sonnet 4.6: ↓ 88.7%
vs GPT-5.4 mini: ↓ 56.5%
#6

Devstral 2
Mistral AI

$0.018200 (rounded ~ $0.02)
vs Claude Sonnet 4.6: ↓ 88.1%
vs GPT-5.4 mini: ↓ 54.2%
#7

Mistral Large 3
Mistral AI

$0.023500 (rounded ~ $0.02)
vs Claude Sonnet 4.6: ↓ 84.6%
vs GPT-5.4 mini: ↓ 40.9%
#8

Gemini 3.8 Flash
Google

$0.038250 (rounded ~ $0.04)
vs Claude Sonnet 4.6: ↓ 75%
vs GPT-5.4 mini: ↓ 3.8%
#9

GPT-5.4 mini
OpenAI

$0.039750
vs Claude Sonnet 4.6: ↓ 74%
vs GPT-5.4 mini: Same
#10

Claude Haiku 4.5
Anthropic

$0.051000 (rounded ~ $0.05)
vs Claude Sonnet 4.6: ↓ 66.7%
vs GPT-5.4 mini: ↑ 28.3%
#11

GPT-5.6 Luna
OpenAI

$0.053000 (rounded ~ $0.05)
vs Claude Sonnet 4.6: ↓ 65.4%
vs GPT-5.4 mini: ↑ 33.3%
#12

Gemini 3.6 Flash
Google

$0.076500 (rounded ~ $0.08)
vs Claude Sonnet 4.6: ↓ 50%
vs GPT-5.4 mini: ↑ 92.5%
#13

Gemini 3.5 Flash
Google

$0.079500
vs Claude Sonnet 4.6: ↓ 48%
vs GPT-5.4 mini: ↑ 100%
#14

Claude Sonnet 5
Anthropic

$0.102000 (rounded ~ $0.10)
vs Claude Sonnet 4.6: ↓ 33.3%
vs GPT-5.4 mini: ↑ 156.6%
#15

Gemini 3.1 Flash
Google

$0.106000 (rounded ~ $0.11)
vs Claude Sonnet 4.6: ↓ 30.7%
vs GPT-5.4 mini: ↑ 166.7%
#16

GPT-5.6 Terra
OpenAI

$0.132500 (rounded ~ $0.13)
vs Claude Sonnet 4.6: ↓ 13.4%
vs GPT-5.4 mini: ↑ 233.3%
#17

Claude Opus 4.7
Anthropic

$0.255000 (rounded ~ $0.26)
vs Claude Sonnet 4.6: ↑ 66.7%
vs GPT-5.4 mini: ↑ 541.5%
#18

Claude Opus 5
Anthropic

$0.255000 (rounded ~ $0.26)
vs Claude Sonnet 4.6: ↑ 66.7%
vs GPT-5.4 mini: ↑ 541.5%
#19

Claude Opus 4.8
Anthropic

$0.255000 (rounded ~ $0.26)
vs Claude Sonnet 4.6: ↑ 66.7%
vs GPT-5.4 mini: ↑ 541.5%
#20

Claude Opus 4.6
Anthropic

$0.255000 (rounded ~ $0.26)
vs Claude Sonnet 4.6: ↑ 66.7%
vs GPT-5.4 mini: ↑ 541.5%
#21

GPT-5.4
OpenAI

$0.265000 (rounded ~ $0.27)
vs Claude Sonnet 4.6: ↑ 73.2%
vs GPT-5.4 mini: ↑ 566.7%
#22

GPT-5.4 Thinking
OpenAI

$0.265000 (rounded ~ $0.27)
vs Claude Sonnet 4.6: ↑ 73.2%
vs GPT-5.4 mini: ↑ 566.7%
#23

Gemini 2.5 Pro
Google

$0.265000 (rounded ~ $0.27)
vs Claude Sonnet 4.6: ↑ 73.2%
vs GPT-5.4 mini: ↑ 566.7%
#24

GPT-5.5 Instant
OpenAI

$0.265000 (rounded ~ $0.27)
vs Claude Sonnet 4.6: ↑ 73.2%
vs GPT-5.4 mini: ↑ 566.7%
#25

GPT-5.6 Sol
OpenAI

$0.265000 (rounded ~ $0.27)
vs Claude Sonnet 4.6: ↑ 73.2%
vs GPT-5.4 mini: ↑ 566.7%
#26

Grok 4.3
xAI

$0.360000
vs Claude Sonnet 4.6: ↑ 135.3%
vs GPT-5.4 mini: ↑ 805.7%
#27

Grok 4.20 Beta
xAI

$0.360000
vs Claude Sonnet 4.6: ↑ 135.3%
vs GPT-5.4 mini: ↑ 805.7%
#28

Gemini 3.1 Pro
Google

$0.400000
vs Claude Sonnet 4.6: ↑ 161.4%
vs GPT-5.4 mini: ↑ 906.3%
#29

Claude Fable 5.1
Anthropic

$0.502500 (rounded ~ $0.50)
vs Claude Sonnet 4.6: ↑ 228.4%
vs GPT-5.4 mini: ↑ 1164.2%
#30

Claude Mythos 5.1
Anthropic

$0.502500 (rounded ~ $0.50)
vs Claude Sonnet 4.6: ↑ 228.4%
vs GPT-5.4 mini: ↑ 1164.2%
#31

Claude Fable 5
Anthropic

$0.510000
vs Claude Sonnet 4.6: ↑ 233.3%
vs GPT-5.4 mini: ↑ 1183%
#32

Claude Mythos 5
Anthropic

$0.510000
vs Claude Sonnet 4.6: ↑ 233.3%
vs GPT-5.4 mini: ↑ 1183%
#33

GPT-5.5
OpenAI

$1.000000
vs Claude Sonnet 4.6: ↑ 553.6%
vs GPT-5.4 mini: ↑ 2415.7%
#34

GPT-6 Astra
OpenAI

$2.040000
vs Claude Sonnet 4.6: ↑ 1233.3%
vs GPT-5.4 mini: ↑ 5032.1%
#35

GPT-6 Astra
OpenAI

$2.040000
vs Claude Sonnet 4.6: ↑ 1233.3%
vs GPT-5.4 mini: ↑ 5032.1%
✨ How recommendations work (v8.6.0): We scan all active models in the registry and only include those that support ALL your current inputs. For token-based models, we check if they can handle your token counts. For special pricing models (OCR, video, audio), we verify they have the correct pricing structure. Features marked requested were in your inputs but not supported by that model. Now using official provider pricing without reseller markups.

For healthcare administrators producing high-quality video content, the choice between Claude Sonnet 4.6 and GPT-5.4 Mini depends largely on the complexity of your script requirements. Claude Sonnet 4.6 is frequently favored for long-form medical content where precise, nuanced language is critical. It excels at maintaining a consistent tone across complex clinical topics, ensuring that patient-facing explanations remain accurate without sacrificing readability. If your scripts require synthesizing dense medical literature into accessible, empathetic narratives, Sonnet’s reasoning capabilities provide a significant advantage.

GPT-5.4 Mini, conversely, is an ideal choice for high-volume, iterative video production. When you need to rapidly generate multiple drafts for different platforms or audiences, its responsiveness and efficiency are unmatched. It handles structured formatting exceptionally well, which can streamline the transition from script to production software. For administrators juggling multiple video campaigns, GPT-5.4 Mini offers a streamlined workflow that helps maintain a consistent cadence.

Both models are highly capable, but they serve different phases of the production cycle. Use Claude Sonnet 4.6 when the script demands deeper editorial oversight and intricate medical accuracy. Opt for GPT-5.4 Mini when the priority is rapid, large-scale output that keeps your content pipeline moving efficiently. Understanding these qualitative strengths allows you to build a more resilient and cost-effective documentation strategy for your healthcare communication.

Frequently Asked Questions

How accurate are these AI model cost calculations?
Our calculations are based on official pricing from each provider (Google, OpenAI, Anthropic, Meta, xAI, Perplexity, DeepSeek, Mistral) and are updated regularly. We account for all factors including multimodal inputs, caching discounts, batch API pricing, tool usage multipliers, OCR processing, audio minutes, silence fees, and research mode pricing. Note: Reseller markups and dedicated instance multipliers have been removed to reflect official provider pricing.
How does prompt caching work?
Caching discounts vary by provider: Google and OpenAI offer 90% discounts on cached input tokens. Anthropic uses write (1.25x) and read (0.10x) multipliers. Savings are applied to the token portion only, not unit-based fees.
How do Market Recommendations work (v8.6.0)?
Our recommendation engine scans the entire model registry and only includes models that support ALL your current input parameters (tokens, images, video, audio, OCR, tools, batch API, etc.). It calculates exact costs with your settings and sorts by price, showing you the best value options that can handle your complete workflow. Special pricing models (OCR, video, audio, image generation) are properly handled and only appear when their specific input types are requested. v8.6.0 removes reseller markups (20% buffer) and dedicated instance multipliers to reflect official provider pricing.
What is the YemHub AI Calculator Tool?
The YemHub AI Calculator is the most comprehensive tool for estimating costs and comparing performance metrics across 50+ AI models. It calculates token-based pricing, analyzes multimodal processing, accounts for state-dependent pricing (context cliffs, tiered tunnels), provides optimization recommendations, and now offers intelligent market matching to find the best alternatives for your specific needs.